Fact · Accessibility and health
100milligrams per day
A 2007 clinical review reports that the upper limit for daily vitamin B6 has been set at 100 mg a day.
Checked against its source on October 17, 2026
In the source's own words
“the upper limit (UL) has been set at 100 mg/d”
Carpal tunnel syndrome and vitamin B6, Milly Ryan-Harshman and Walid Aldoori, Canadian Family Physician, 2007, Recommendations on vitamin B6 supplementation.
Open the original- What it measures
- The review gives this limit in its section on supplement recommendations, alongside the statement that the main toxicity of pyridoxine is sensory neuropathy.
- What it does not show
- A tolerable upper intake level for daily supplements, not a dose that treats carpal tunnel syndrome. The same section notes that most studies found no neuropathy at doses between 40 and 500 mg a day, so the limit is a safety margin rather than a treatment dose. Check the current figure with a clinician or pharmacist before taking any high-dose supplement.