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A 2024 narrative review says the clinical picture of carpal tunnel syndrome during pregnancy is mainly shaped by hormonal changes, posture, weight gain and fluid retention.
Checked against its source on October 17, 2026
In the source's own words
“The clinical picture of PRCTS is primarily determined by hormonal changes, postural modifications, weight gain and fluid retention”
Management of "De Novo" Carpal Tunnel Syndrome in Pregnancy: A Narrative Review, Maria-Cristina Cîmpeanu et al., Journal of Personalized Medicine, 2024, Section 2, Clinical Findings and Diagnosis.
Open the original (DOI 10.3390/jpm14030240)- What it measures
- The review links the hormonal changes to raised blood levels of oestrogen, aldosterone, cortisol, prolactin and glucose. It also describes the fluid retention as causing swelling, mainly through reduced venous return.
- What it does not show
- A narrative review, not a trial. It does not measure how much each factor contributes, and the strongest measured link to fluid is the Dutch cohort's odds ratio of 1.8.