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A 2004 review of vitamin B6 sold without prescription warns that mega-doses of the vitamin may result in intoxication.

Checked against its source on October 17, 2026

In the source's own words

“Mega-doses of this vitamin may result in intoxication.”

Vitamin B6 (Pyridoxine)--excessive dosage in food supplements and OTC medications, N. Barak et al., Harefuah, 2004, Abstract.

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What it measures
The review covers vitamin B6 sold as a supplement and over the counter, and notes that high intake is found in patients with carpal tunnel syndrome, among other conditions.
What it does not show
The English abstract does not give a dose threshold, and the article is in Hebrew. Read it as a warning about high doses, not as a safe limit.

Source

Cited on

Vitamin B6 mega-doses can cause intoxication | Yap