Fact · Accessibility and health
A 2004 review describes the idea that idiopathic carpal tunnel syndrome is a sign of vitamin B6 deficiency as a hypothesis, not as an established cause.
Checked against its source on October 17, 2026
In the source's own words
“It has been hypothesized that idiopathic carpal tunnel syndrome (CTS) is a manifestation of vitamin B6 deficiency.”
Pyridoxine hydrochloride treatment of carpal tunnel syndrome: a review, E. Aufiero et al., Nutrition Reviews, 2004, Abstract.
Open the original (DOI 10.1111/j.1753-4887.2004.tb00030.x)- What it measures
- The review examined whether pyridoxine (vitamin B6) supplements treat carpal tunnel syndrome. It sets out the competing explanations for any effect.
- What it does not show
- The word hypothesized is the review's own. It describes the claim before testing it, and the review finds that few studies measured B6 levels.