Preprint
An accurate and rapidly calibrating speech neuroprosthesis
Nicholas S. Card et al., medRxiv preprint, deposited in PubMed Central (later published in the New England Journal of Medicine, 2024), 2024 · DOI 10.1101/2023.12.26.23300110
Read the originalRead on October 17, 2026
- What it is
- The BrainGate2 study of one man with ALS, implanted with 256 intracortical electrodes, who attempted to speak while the system decoded his neural activity into words on a screen. The paper reports accuracy on a 50-word and then a 125,000-word vocabulary, and the speed of a copy task.
- How much weight it carries
- Peer-reviewed in its published form, but the copy used here is the open preprint copy in PubMed Central. Results come from one participant, in a clinical trial setting with supervised training sessions, so they describe what is possible rather than a product. The speed figure is for a copy task, not free conversation.
Facts taken from this source
- In the 2024 BrainGate study, the speech neuroprosthesis sustained 97.5 percent accuracy beyond eight months after surgery.
“sustained 97.5% accuracy beyond eight months after surgical implantation” (Abstract)
- In a 2024 BrainGate study, one participant's copy task was decoded at his self-paced speaking rate of 31.6 words per minute.
“at the participant’s self-paced speaking rate of 31.6 words per minute” (Results, copy task in the final five evaluation sessions)
- In the 2024 BrainGate study, the participant typed with a gyroscopic head mouse at 6.3 correct words per minute, with a standard deviation of 1.3.
“His typing speed using his gyroscopic headmouse (Zono 2, Quha, Nokia, Finland) is 6.3 ± 1.3 correct words per minute” (Results, participant background and typing speed)